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In subjects who smoked more than ten cigarettes per day, the risk was twice that of non-smokers/former smokers, according to Cox proportional hazards regression (Yen et al., 2014)

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To ensure a consistent approach to civil money penalties, CMS proposes applying existing appeal procedures for civil money penalties in 42 CFR 423, subpart T of this title to manufacturers appealing a civil money penalty imposed under the Medicare Part B Drug Inflation Rebate Program