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By 2030 Philip Morris International predicts that their sales of Zyn will hit $3.5 billion

These estimates are concerning as tobacco use has consistently been associated with numerous chronic diseases and adverse health outcomes, including possible mutagenic effects (World Health Organization 2020)

Compared with never-smokers, participants who smoked 12 or 35 cigarettes per day were at higher risk of all-cause mortality even after adjustment for demographic variables, lifestyle factors and physician-diagnosis of chronic disease