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Future Pharmacotherapeutic Approaches to Treat Nicotine Addiction Both the neurochemical and functional changes observed in adolescent brain regions are associated with dopamine modulation and the cerebral reward system, which are influenced by specific genes, suggesting that a genetic predisposition of the neural mechanisms is involved in the acquisition of dependence in nicotine addiction

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For this study, data were collected in 2014 from ITC participants in Mexico City, Guadalajara, and Monterrey, the three largest cities in Mexico

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