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Even among studies in which PCS were used, a persistent limitation is that sex differences in PCS were not considered

And the fact that you can have the federal level still have one set of rules and the state rules, theres definitely a paradox there that got to be resolved at some point. The conversation, noted earlier by CelebStoner, also turned to cannabis potency, with Gates observing that a lot of us who were smoking when it was illegal, the dosage was actually pretty modest. So at least as you move into this legal pot world, you can be getting like really extreme doses, particularly on the edibles, he said

In the pre-ban period, users primarily discussed practical concerns such as locating reliable vendors, taking advantage of sales, and managing discontinued flavor lines or routine shipping delays

PMID 12054329