If you want to go to a conference, present an abstract or submit a paper, the first thing they ask is: Are you related to a tobacco company? If I am then very honest, I have to say yes, Van den Bosch explained
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The meta-analytic tool overcomes many of the limitations of traditional meta-analyses by incorporating between-study heterogeneity into the uncertainty of risk estimates, accounting for small numbers of studies, relaxing the assumption of log(linearity) applied to the risk functions, handling differences in exposure ranges between comparison groups, and systematically testing and adjusting for bias due to study designs and characteristics