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Smoking appears to have both causal relationships and possible synergistic interactions with other major risk factors for coronary heart disease, including hyperlipidemia, hypertension, and diabetes mellitus [ 54 ]

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Overexpression of miR - 145 , miR - 149 , miR - 150 or miR - 218 suppressed the secretion of inflammatory cytokines that had been induced by CS through the inactivation of the NF - B signaling pathway [187,188,189, 192]

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