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To note, similar reductions in endothelial-dependent dilation have been identified after a single exposure to combustible tobacco products or e-cigarettes [115], although contradictory results are also available, supporting that acute exposure to neither combustible tobacco cigarettes nor ENDS had an effect on vascular function [87]

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While HWLs must comply with their countrys requirements to maximize the public health impacts of HWLs, high compliance with policies that involve inadequate requirements is also a key issue to be addressed