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A range of approaches have been used by others, from using the exposure prevalence of control subjects in casecontrol studies (IARC, 2007) to extrapolation from exposure of children to ETS at home (Jamrozik, 2005)

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When AS is the reason for a TAVR admission, principal diagnosis is typically I35.0 and the procedure drives MS-DRG 216221 (cardiac valve procedures)

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