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The primary mechanism questioned to explain these findings is the induction that smoking might have on the activity of liver enzymes, particularly CYP1A2, which is responsible for the metabolism of these medicines at the liver level [15, 19]
However, this rate varies depending on sex and weight
CHAKRABARTI: Understood
After the case wound through appeals, Kessler issued a revised opinion and order in February reiterating that tobacco companies must make the following corrective statements on their websites and in advertising: Many smokers switch to low-tar and light cigarettes rather than quitting because they think low-tar and light cigarettes are less harmful
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