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It is tempting to speculate that an attenuated anti-oxidant response with elevated ROS in COPD [21, 22, 28, 36] may lead to an increased oxidant burden, possibly contributing to the observed mitochondrial defects in bronchial epithelial cells from COPD patients [6, 32, 37]

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The nations largest tobacco company, Altria, said it will carefully review the proposed rule. The company, which makes Marlboro cigarettes, was not part of the industry lawsuit

But the claim that they are in the business of ending traditional cigarettes is premature at best, and insincere at the worst. While cigarette smoking may be on the decline, the habit still supports a booming industry with plenty of buyers