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In keeping with a classification scheme based on FDAs public health standard, and recognizing that decision-makers must often act in the face of scientific uncertainty, we asked whether the evidence in a particular area was sufficient to conclude that a relationship was more likely than not, whether the evidence shows that a relationship was at least as likely as not, whether the evidence is insufficient to conclude that a relationship was more likely than not, or whether there was insufficient evidence to make a determination of strength of evidence

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higher blood pressure), and either similar or better outcomes to people who smoke regular cigarettes