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Given the ongoing debates about the health implications of electronic cigarette use, this systematic review aims to thoroughly investigate the direct effects of electronic cigarette use on human health, considering the characteristics of the populations studied and the duration of exposure

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Our multimodal meta-analytic outcomes add to a growing literature implicating the vmPFC, insula, and thalamus as contributors to the initiation, escalation, maintenance, and/or cessation of cigarette smoking

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