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Together these factors can compromise the restrictive properties of the bloodbrain barrier (BBB) and trigger the pathogenesis/progression of several neurological disorders including silent cerebral infarction, stroke, multiple sclerosis and Alzheimers disease

Ads that provide self-affirming messages (e.g., the value of raising a family or maintaining health) might buffer against defensive processingdismissal of a health message perceived as personally threateningbecause it has been shown that self-affirmation prior to exposure to graphic images on cigarette pack warnings reduces such defensive processing [41]