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The test is designed to be straightforward to administer, requiring minimal time and effort from both the participant and the administrator

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Nicotine is the only gateway substance for which a direct molecular mechanism of cross-sensitization has been experimentally verified in peer-reviewed research, distinguishing it from alcohol and cannabis, whose human gateway effects remain primarily epidemiological

(CNN) -- Five tobacco companies, including some of the largest in the United States, filed a lawsuit against the federal government on Tuesday, alleging that government-mandated graphic warning labels on cigarette packages unconstitutionally infringe on the companies' rights