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Harm Reduction When reviewing the evidence on what is known about e-cigarette exposure and health effects compared with conventional tobacco cigarettes, the committee found: Conclusive evidence that completely substituting e-cigarettes for conventional cigarettes reduces user exposure to numerous toxic substances and carcinogens present in conventional cigarettes

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However, e-cigarettes can also cause nicotine dependence, so users may need treatment for nicotine dependence similar to that for tobacco users

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