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In response, the brain releases dopamine, a substance that induces feelings of pleasure

cigarette smokers had successfully quit smoking in the wake of the 1964 Surgeon Generals report and no one else started smoking, an estimated 2.5 million people would have not died from lung cancer (1.6 million men and 883,000 women would not have been diagnosed with the disease)

[33] Due to their similarity to traditional cigarettes, e-cigarettes could play a valuable role in tobacco harm reduction