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How smoking affects bones Stitzlein, an assistant professor and chief of orthopedic oncology in the UCI School of Medicines Department of Orthopaedic Surgery, explains several ways smoking weakens bones: Smoking reduces the blood supply to the bones and to many other body tissues

[38] The increase in platelet aggregation, the effect of nicotine on blood coagulation time, and the increase in blood viscosity, in combination with the increase in levels of LDL and VLDL, the reduction in HDL, and inflammatory processes, promote the creation of atheromatous plaque and the development of atherosclerosis ( Figure 1 )