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The same group plans similar studies in North Carolina, where tobacco restrictions have traditionally been less strict, and in New York City, where they have been more stringent

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Kreteks have also been linked to an increased risk of acute lung injury, including inflammation, pulmonary fluid, and low oxygen levels

39,40 Importantly, these studies did not take into consideration important COPD exacerbation risk confounders such as smoking abstinence duration, severity of COPD, comorbidities, and age