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13 A modest increase in BC prevalence was observed with every additional 20 pack-years, and the hazard ratio increased, which was dependent on the quantity, duration, and initial age of CS

However, it can also be unintentionally produced during the manufacturing process and may be found in low levels in tobacco smoke and chewing tobacco, certain foods, cosmetics, detergents, pesticides, and other products, according to the Agency for Toxic Substances & Disease Registry

Migraine headaches Migraine headaches are known by their intense, throbbing pain, often on one side of the head

Overall health: Habitual use of chewing tobacco has also been linked with high blood pressure, blurred vision and dizziness