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These systematic bias control procedures were employed for the purpose of bolstering the internal validity of associations observed and the minimization of spurious results based upon methodological limitations, thus maximizing the overall scientific rigor and interpretability of results within the framework of e-cigarette health impact studies

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Take a look at the Surgeon General's on Tobacco Use

Some parents/caregivers think the skin looks swollen or bubbling and the scar requires urgent care, but there is no emergency