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In a statement, the FDA said Juuls application left regulators with significant questions and didnt include enough information to evaluate any potential risks

doi:10.1016/j.drugalcdep.2011.12.018

So even in the paper they said there was no hard evidence for what they were suggesting. In terms of the long-term impacts, Prof Cox cited research published earlier this year in the New England Journal of Medicine on ex-smokers who used e-cigarettes over a couple of years

These two factors have contributed to destroy the positive image of these products, to shift the perceptions of consumers from benefit to harm and as a consequence - to the collapse of the e-cig market in that country