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Marlboro Owner: Philip Morris (USA), Philip Morris International Country of origin: United States of America Established: 1924 Brand Value: $32.7 billion It all started in Bond Street, London, where in 1873, British tobacconist Phillip Morris opened a shop selling tobacco and rolled cigarettes

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First author, Dr Kate Gowers (Lungs for Living Research Centre at UCL), said: Our study is the first time that scientists have looked in detail at the genetic effects of smoking on individual healthy lung cells