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As mentioned above, nicotine selectively activates nicotinic acetylcholine receptors (nAChRs), particularly those containing the 42 and 7 subunits, which in turn modulate dopamine, glutamate, serotonin, gamma-aminobutyric acid (GABA), and acetylcholine pathways associated with enhanced cognitive processing

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Although never launched, Project SCUM shined a light on internal company views of targeted communities and their hopes of securing a youthful population of lifetime smokers