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Conclusion: An Estimate, Not an Exact Science In summary, while its impossible to give a single, universally accurate number, current understanding suggests that for common nicotine salt-based disposable vapes and pod systems, approximately 10-15 puffs of a 5% (50mg/ml) nicotine e-liquid or 15-25 puffs of a 2% (20mg/ml) nicotine e-liquid might deliver a roughly comparable amount of absorbed nicotine to one traditional cigarette

This is usually done with an injection into your glutes, however if you are allergic to penicillin there are other options