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DOI: 10.1371/journal.pone.0289058 Funding: NN is supported by the California Tobacco-Related Disease Research Program (grants T31FT1564 and T32KT5071) and the National Center for Advancing Translational Sciences, National Institutes of Health, through UCSF Clinical and Translational Science Institute (grant UL1 TR001872-06)

Murine studies, in particular, often employ smoke exposure protocols that differ significantly from human smoking behaviors, such as variations in smoke composition, exposure methods, and involuntary exposure patterns