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The gateway to smoking hypothesis, meanwhile, may well fall foul of most of the statistical evidence as well as common-sense objections, but it is nevertheless a belief that cannot be ignored

The flowchart of inclusion/exclusion of related countries is shown in Supplementary eFigure 1

We also investigated relationships between clinical characteristics such as age, gender, BMI increase, successful smoking cessation, and alcohol drinking habits and newly-developed GERD 1 year after smoking cessation in patients who had not had GERD at the first visit

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