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Post-treatment, clinical parameters (gingival colour and consistency, plaque index, bleeding on probing [BoP], PPD, keratinised tissue width) and salivary inflammatory biomarkers (MMP-8, IL-6, IL-1, TIMP-1) were assessed at three time points: one month, six months, and one year

The FDA will take comments before issuing final rules, which then could face years of legal challenges from deep-pocketed tobacco companies

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