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Nicotine induces proinflammatory responses in macrophages and the aorta leading to acceleration of atherosclerosis in low-density lipoprotein receptor (-/-) mice

A member of the National Theatre Company at The Old Vic from 1972 to 1975, Rigg took leading roles in premiere productions of two Tom Stoppard plays, Dorothy Moore in Jumpers (National Theatre, 1972) and Ruth Carson in Night and Day (Phoenix Theatre, 1978)

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However direct exposure from cigarette smoke represents only a portion of the oxidative stress experienced by smokers