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At high doses, low blood pressure, irregular and weak pulse, breathing difficulties, convulsions, cardiovascular collapse and extreme fatigue may be added Precautions for use of Nicotine EG 1mg/dose Spray Do not use if you are under 18 years of age, if you have never smoked or if you are allergic to nicotine or any of the components of this solution

This is a statistically greater decrease in rates compared to rates of substance use in pregnancy in California and in the U.S