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Studies were included if they involved: OST users of any gender (population), assessed NRT as the intervention, had placebo, no intervention, or other behavioral support interventions (comparison), reported 7-day point prevalence OST abstinence or reduction at week 12 (outcome) and published randomized and non-randomized trials in English between 2004 and June 2024 (study designs)

But, a Centers for Disease Control and Prevention (CDC) investigation finds 77 percent of those patients report vaping tetrahydrocannabinol (THC), the primary psychoactive ingredient in marijuana

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