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[1] Comprehensive definitions should cover all e-cigarette products, including all types of e-cigarettes as well as their components and parts, regardless of the substance that is inhaled or its source, and are also broad enough to cover future e-cigarette products

Notes 9 , 88 (2016)

However, inhalation of toxins by smoking disturbs the ability of the proper functioning of the defences and upsets the immune system leading to inflammation in the airways

The severity of nicotine withdrawal symptoms will vary based on the level of the persons addiction, but they may include: Tobacco cravings Anxiety Depression Drowsiness Irritability Nausea Restlessness Headaches Increased appetite/weight gain Sweating Intestinal cramping Difficulty concentrating More Time