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Survey after survey shows [that] when you ask people who have tried e-cigarettes what [they tried] for, one big chunk says to quit smoking and another big chunk says to reduce smoking, said Jonathan Foulds, PhD, professor of public health sciences and psychiatry at Penn State College of Medicines Cancer Institute

Greek researchers said e-cigarettes - battery-powered metal tubes that transform liquid laced with nicotine into vapour - had no adverse effects on cardiac function in their small trial

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In vitro studies have shown that activation of MRGPRX2 or its murine ortholog MrgprB2 induces MCs degranulation via Orai channels, with Orai1 and Orai2 being the predominant contributors