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Additional co-authors on the study include: Brian Dang, M.S., Sara B

Exceptions to this, such as North Shore, which was cytotoxic (51% of control) but did not have a cytotoxic level of flavor chemicals, suggest that our target list of chemicals does not contain some of the flavor chemicals that are used in refill fluids, that chemicals act additively or synergistically to produce cytotoxicity, or that another factor, such as a metals 19 , caused cytotoxicity in this product

As the FDA routinely does with regard to the many products it regulates, I believe the agency will ultimately address that uncertainty in the best interest of people who smoke. The FDA still has to rule on PMIs modified-risk tobacco product (MRTP) application, as well as its larger, separate application to sell iQOS in the United States

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