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Scientific reviews and regulatory documents have explored how additives affect pyrolysis products, nicotine delivery, and sensory smoothness. This is one reason cigarette discourse so often focuses on chemistry and policy

27 June 2008

Therefore it seems that nicotine harms should not be exaggerated when legitimate concerns are framed, for example with concerns raised by animal studies but scant human evidence that it causes permanent brain damage when decoupled from all the other toxins in inhaled smoke or that nicotine itself either causes or strongly promotes cancer

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