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The results were consistent across all characteristics examined in the randomized trial, including demographics, nicotine dependence, social influences to vape, mental health symptoms, and other substance use

For many tobacco users, repeated exposure alters the brains sensitivity to dopamine and eventually leads to addiction

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It happens due to prolonged sitting on the bike saddle, repetitive pedaling motion, or incorrect bike fit especially if they have poor flexibility or muscle imbalances in the hips and glutes