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Specifically, adults born in the 1950 s, 1960 s, and 1970 s had the highest likelihood of smoking, while the three oldest (1899, 1904, 1909) birth cohorts, as well as the most recent (1999) birth cohort, showed the lowest probability of cigarette use
The conclusions are based on a synthesis of: clinical data (biomarkers in humans showing DNA damage, oxidative stress, and #inflammation), animal studies (including lung #tumor development in mice), laboratory research (cellular damage and disrupted biological pathways)
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