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As the evidence for the lethal impact of tobacco products started mounting, the companies created uncertainty and dispute regarding health risks while putting filters on cigarettes and promised research into the health effects of smoking to address growing public concern

Senate, 10 Republican members of the U.S

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Some studies suggest that priming peripheral blood mononuclear cells (PBMCs) with urate enhances the release of interleukin-1 (IL-1) in response to lipopolysaccharide (LPS), indicating a potential pro-inflammatory effect