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In addition, genes involved in tight junctions formation, intraflagellar transport gene and cilia-related genes are markedly down-regulated in the airway epithelium of healthy smokers when compared with nonsmokers [131]

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Finally, most of these "shock" headline stories proclaiming the dangers of vaping NEVER compare e-cigarettes to smoking traditional tobacco cigarettes

Dimensionality reduction, clustering, and visualization Before clustering and visualizing each of the two scRNA-seq datasets (in vitro and in vivo), we reduced the dimensionality of variation in a way that accounted for batch-based shifts in expression among donors