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[...] It is reasonable to conclude that if used as a substitute rather than an addition, e-cigarettes are much less harmful than continuing to smoke.[xxi] Cochrane Review : The gold-standard systematic review of randomised controlled trials has concluded that for every 100 people using nicotine ecigarettes to stop smoking, 9 to 14 might successfully stop, compared with only 6 of 100 people using NRT, 7 of 100 using nicotinefree ecigarettes, or four of 100 people having no support or behavioural support only.[xxii] US Federal Drug Administration : The FDA has granted a number of Premarket Tobacco Product Applications (PMTAs)[xxiii] and Modified Risk Tobacco Product orders (MRTPs)[xxiv] for safer nicotine products in the US

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Signs of addiction to chewing tobacco include: Cravings for chewing tobacco Needing higher doses to achieve the same desired effect Experiencing withdrawal symptoms when cutting back or going without Irritability or anger Anxiety or restlessness Avoiding activities where they cant use chewing tobacco Difficulty concentrating Insomnia Increased appetite or weight gain when not using Continuing to use chewing tobacco despite negative side effects or health issues Common Strategies for Quitting Chewing Tobacco Due to its addictive nature and accessibility (e.g., chewing tobacco can be used in places where smoking is prohibited), users can become heavily dependent and have a hard time quitting

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