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Pulze does all this at temperatures three times lower than the burning process in a conventional cigarette

The administration has failed to act on guidelines issued under Cigarettes and Other Tobacco Products (Prohibition of Advertisement and Regulation of Trade and Commerce, Production, Supply and Distribution) Act, 2003 (COTPA, 2003)

Some users report dry throat, mild cough, or temporary mouth irritation, particularly in the first weeks of switching from cigarettes

Sample size For a Williams crossover design with three products and six sequences, and an overall standard deviation (SD) of paired differences of 0.129 (comparable to an intra-participant coefficient of variation [CV] of 13%), it was calculated that a minimum of 30 participants would be needed to detect an 11% (0.11) difference between mean values with a statistical power of at least 80% and a significance level of 5%