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Key Ways Smoking Harms the Kidneys Narrows blood vessels, reducing kidney blood flow Increases blood pressure, a major risk factor for kidney disease Promotes inflammation and oxidative stress Accelerates decline in kidney filtration rate (eGFR) Increases protein leakage in urine (proteinuria) These effects gradually weaken kidney function and may lead to chronic kidney disease if smoking continues over time

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The National Institute on Drug Abuse (NIDA) recommends behavioral treatments such as Cognitive Behavioral Therapy, Motivational Interviewing, and mindfulness as effective approaches to treating tobacco addiction

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