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The metabolite that remains after your body has broken down the nicotine that you have consumed is called cotinine

Lyon: the International Agency for Research on Cancer, 2012

Creating a smoking machine Researchers engineer instrument that replicates cigarette smokes impact on human airways While it is well known that cigarette smoking is a major cause of lung disease, and a key exacerbating factor for patients suffering from chronic obstructive pulmonary disease (COPD), it has not been possible to effectively model its deleterious effects on human lungs under normal breathing conditions

The harmful chemicals in tobacco smoke can cause genetic mutations and damage to the cells in the respiratory tract, leading to the development of cancerous growths