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In vitro studies demonstrated tissue- and species-specific differences in dominance of either or neither pathway [66, 84, 88], which could account for the nature of DNA damage and signatures of NNK-mediated carcinogenesis

There were also increases in volunteers heart rates (from an average of 66 beats per minute/bpm to an average of 73bpm) and blood pressure (from an average of 108 millimetres of mercury/mmHg to an average of 117mmHg)

The same report also states that the Eastern European country will lose up to $3bn per annum in revenue as menthol smokers will turn to smuggled cigarettes from Ukraine and Belarus

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