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For the correlation between SDI and EAPC, significant negative correlations were observed for tobacco, smoking, and secondhand smoke, while no significant correlations were observed for high alcohol use, drug use, and chewing tobacco

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This is not an exhaustive list of possible drug interactions

Fumigation ( dhupa ) and fire offerings ( homa ) are prescribed in the Ayurveda for medical purposes, and have been practiced for at least 3,000 years while smoking, dhumrapana (literally "drinking smoke"), has been practiced for at least 2,000 years