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Stewart, "Cooperative Efforts Against Bootlegging in the Midwest," Proceedings from the 50th Annual Meetings of the National Tobacco Tax Association , (Chicago: Federation of Tax Administrators, 1976), 76

Researchers found that smoking negatively affected the structural integrity of subcortical brain regions

One study limitation, according to the researchers, is that the analyses were based on self-reported data on ENDS use and ED status, all of which are subject to misclassification and desirability bias (the possibility that respondents will answer questions based on what they think will be perceived favorably by others)