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LEfSe analysis also revealed the differential abundance of Capnocytophaga, Fusobacterium and Campylobacter in tumor site using both Greengenes and SILVA databases ( Supplementary Figures S5C, D

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57,58 Other carbonyls formed upon the thermal degradation of sugars also exhibit carcinogenic properties: formaldehyde and acetaldehyde cause respiratory tumors in laboratory animals, 59,60 and crotonaldehyde is a potent irritant and forms DNA adducts in the human lung

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