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3.1 Endothelial dysfunction Various clinical and laboratory studies have shown that endothelial dysfunction induced by cigarette smoke is mediated by decreased nitric oxide (NO) bioavailability, increased production of superoxide anions, and increased production and release of endothelin ( 28 )

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J Appl Phys 21(6):581591

Proper storage can extend usability beyond expiration dates, while poor storage accelerates deterioration