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Similarly, during influenza A virus infection, e-cigaretteexposed mice showed higher viral titers, worsened illness severity, and increased mortality ( These findings suggest that e-cigarette aerosols weaken host immune defenses, increasing vulnerability to both bacterial and viral pathogensan especially concerning effect in children and adolescents, whose immune systems are still maturing ( 3.2.4 Effects on mental health and neurodevelopment Based on the body of experimental, clinical, and epidemiological evidence examined in this review, the effects of e-cigarettes appear to extend beyond physical health, with significant implications for adolescent brain development and mental health

Cigarettes also give off another form of waste in the form of fumes and smoke which emit pollution into the atmosphere