Certain groups are particularly vulnerable to the harmful effects of secondhand smoke: Children and infants Pregnant women Elderly individuals People with chronic illnesses such as asthma, heart disease, or diabetes Employees in hospitality industries (e.g., bars, casinos, restaurants without smoke-free laws) Health Statistics on Secondhand Smoke Each year, secondhand smoke causes an estimated 41,000 deaths among non-smoking adults and 400 deaths in infants in the United States alone
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Reynolds say they have submitted over 150,000 pages to support its application adding: FDA has issued guidance explaining criteria for PMTA submissions, which make clear that manufacturers must provide not only information on the composition, design and manufacturing process associated with the product, but also chemistry, toxicological and behavioral studies that demonstrate the product when used is appropriate for the protection of the public health
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