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According to a CDC advisory panel that reviews vaccines, the risk-benefit of COVID-19 vaccination is most favorable for people who have at least one high-risk health condition (such as asthma)

Parents then worry about life-threatening attacks, hospitalizations, and the need for quick-relief medication

Kim JS, Choi YY, Jin G, Kang HG, Choi JE, Jeon HS, Lee WK, Kim DS, Kim CH, Kim YJ, Son JW, Jung TH, Park JY: Association of a common AGO1 variant with lung cancer risk: a two-stage casecontrol study

Neither varenicline nor bupropion has shown benefit in the adolescent population based on limited studies of nicotine dependence associated with combustible cigarettes